AKTIVITAS FRAKSI DARI EKSTRAK ETANOL 70% DAUN ROSELA (Hibiscus sabdariffa L.) TERHADAP PENINGKATANJUMLAH ERITROSIT TIKUS ANEMIA

Authors

  • Ani Pahriyani Universitas Muhammadiyah Prof. DR. HAMKA
  • Ema Dewanti Universitas Muhammadiyah Prof. DR. HAMKA

DOI:

https://doi.org/10.22236/semnas/11706-719225

Keywords:

Erythrocytes, Anemic, rosella leaves’ fraction, Hibiscus sabdariffa L.

Abstract

Roselle leaves have been widely used for treatment.one of its efficacy to increase the number of erythrocytes. This study aims to determine the activity fraction of rosellaleaves (Hibiscus sabdariffa L.) on increasing the number of erythrocytes in anemic white male rats. The test was carried out by dividing 25 rats into 5 groups, there were; normal control was not induced and given Na-CMC 0.5%, a group induced NaNO2but not given fraction.water fraction group, ethyl acetate and n-hexane NaNO2 was induced for 18 days and given 1.7412 mg/200g BW from each fraction for 14 days. Blood collection was carried out through the rat's tail and the erythrocyte counted was measured using a hematology analyzer. One way ANOVA was used to analyze the data of erythrocytes’ quantity and continued with tukey test. The results revealed that the water fraction, ethyl acetate fraction and n-hexane fraction of rosella leaves had activity on white male anemic induced by NaNO2. The conclusionvariation of fraction have same activity to increase the number of erythrocytes reached normal erythrocyte.

 

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Published

2020-08-28

How to Cite

Ani Pahriyani, & Ema Dewanti. (2020). AKTIVITAS FRAKSI DARI EKSTRAK ETANOL 70% DAUN ROSELA (Hibiscus sabdariffa L.) TERHADAP PENINGKATANJUMLAH ERITROSIT TIKUS ANEMIA. Prosiding Seminar Nasional Berseri, 1(1), 706–719. https://doi.org/10.22236/semnas/11706-719225